Allogeneic human tissue-engineered blood vessel

Tissue-engineered blood vessel for adult arterial revascularization.

With the rise in obesity and heart disease in the United States and around the world, there is a strong correlation with the need to develop various ways to repair damaged blood vessels. Previous treatments of the repair of blood vessels involved stents and also various forms of synthetic sheaths. However, these treatments had their problems. Problems included movement of the stent, blood clott...

Decellularized tissue-engineered blood vessel as an arterial conduit.

Arterial tissue-engineering techniques that have been reported previously typically involve long waiting times of several months while cells from the recipient are cultured to create the engineered vessel. In this study, we developed a different approach to arterial tissue engineering that can substantially reduce the waiting time for a graft. Tissue-engineered vessels (TEVs) were grown from ba...

Tissue engineering of blood vessel

Vascular grafts are in large demand for coronary and peripheral bypass surgeries. Although synthetic grafts have been developed, replacement of vessels with purely synthetic polymeric conduits often leads to the failure of such graft, especially in the grafts less than 6 mm in diameter or in the areas of low blood flow, mainly due to the early formation of thrombosis. Moreover, the commonly use...

Manufacturing and Mechanical Testing of Biochemically Stimulated Tissue-engineered Blood Vessel Constructs

Development and Implementation of Assessment Methods for Tissue-Engineered Blood Vessel Mimics